CODDHI 2011-FOCO DM1-Avaliação temporal do diagnóstico do DM1: cetoacidose diabética vs glicemia em jejum, casual e TOTG

Este painel de discussão contou com a explanação do Dr Carlos Negrato sobre a abordagem diagnóstica no DM1.
Segundo o Dr. Negrato, por ser o DM1 uma doença com altas taxas de morbi-mortalidade, até o momento, não é possível curar ou reverter.
A incidência do DM1 aumenta em média 6,6% ao ano e no Reino Unido, além do aumento da incidência, tem se observado que o pico do diagnóstico tem reduzido para os 4 anos de idade, conforme referência do Lancet 2009; 373: 2027-33.
Comentou ainda que, nos últimos anos, o padrão fenotípico da criança com DM1 tem mudado de magro para sobrepeso ou obesidade. No Brasil, 27,7% dos DM1 apresenta sobrepeso ou obesidade.
Foi apresentado um estudo realizado em Bauru (J Endocrinol Invest. 2010 Jun;33(6):373-7) que demonstrou que a maioria dos diagnósticos foi feita em meses com temperaturas mais baixas. Mostra ainda que existe uma pequena prevalência no sexo feminino, porém sem significância estatística e que o diagnóstico ocorre em torno dos 8 anos de idade.
A cetoacidose diabética (CAD) ainda é a principal “forma” de diagnóstico do DM1 e é a principal causa de morbi-mortalidade nesta patologia. É mais freqüente em crianças menores de 4 anos e sem antecedentes familiares de DM. A prevalência de CAD no Brasil é muito alta e está inversamente relacionada com idade e classe social e a principal causa de mortalidade na CAD é o EDEMA CEREBRAL.
Concluiu que, ultimamente, tem sido observada uma mudança de paradigma, uma vez que a incidência de DM1 vem aumentando enquanto ocorre uma diminuição na incidência de CAD.

Esta entrada foi publicada em Diabetes Tipo 1. Adicione o link permanenteaos seus favoritos.

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